Time line

1452	Leonardo is born on April 15 in the village of Anchiano, near the town of Vinci.
1467	At 15 Leonardo is sent to Florence to work as apprentice to Andrea De Verrocchio.
1472	20 year-old Leonardo is accepted into the painters' guild of Florence.
1476	Leonardo is accused of sodomy; he is publicly humiliated although the charges are later dropped.
1478	The Annunciation is painted. The work, initially credited to Da Vinci, is now believed to have been painted by Lorenzo di Credi.
1481	Leonardo begins work on The Adoration of the Magi, an altarpiece for the Monastery of San Donato at Scopeto. He sketches many studies.
1482	Leonardo moves to Milan to work in the service of the city's duke, Ludovico Sforza. He gains the title of "painter and engineer of the duke.
1483	Leonardo paints the Virgin of the Rocks.
1485	Leonardo paints Lady with an Ermine.
1495	Leonardo begins work on The Last Supper in the refectory of the convent of Santa Maria delle Grazie in Milan.
1498	The Last Supper is completed.
1499	With the duke Ludovico Sforza'a fall from power, Da Vinci leaves Milan and spends a short time in Venice.
1500	Leonardo begins painting the Virgin and Child with Saint Anne, a project that he only finishes after 10 years.
1500	Leonardo returns to Florence.
1502	Leonardo begins work as senior military architect and general engineer for Cesare Borgia, son of Pope Alexander VI.
1503	Leonardo is commissioned to paint the Mona Lisa.
1503	Leonardo is commission to paint a mural for the council hall in Florence's Palazzo Vecchio, which is to be the Battle of Anghiari, a work that would remain unfinished.
1515	Leonardo paints St. John the Baptist.
1516	The king of France invites Leonardo to come work for him.
1519	May 2, Leonardo dies in France.

http://www.davincilife.com/timeline.html